1. 2008년 4월 국내 연구논문 발표 실적
  2008년 4월 한달 동안 PubMed에 등록된 국내 생물정보학 관련 발표 논문(제1 저자를 기준으로 한국에서 발표한 논문을 대상으로 12가지의 생물정보학 관련 keyword로 검색하여 정리한 결과)

2. 국외 뉴스
2008년 4월 주요 국외 뉴스 클리핑

날짜	내용
4월 29일	Scientists form International Cancer Genome Consortium Scientists join together to form the International Cancer Genome Consortium, one of most ambitious biomedical research efforts since the Human Genome Project. The consortium will help to coordinate current and future large-scale projects to understand the genomic changes involved in cancer. This genomic information will accelerate efforts to develop better ways of diagnosing, treating and preventing many types of cancer.
4월 18일	Beijing Genomics Institute adds AB SOLiD system to its next generation sequencing technologies The Beijing Genomics Institute announced today that BGI has added Applied Biosystems SOLiD System to BGI's rapidly expanding next-generation sequencing technologies.
4월 10일	Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing Following an outbreak or a bioterrorist attack, standard DNA sequencing and analysis of a pathogen genome for rapid identification of genetic changes or manipulations is time-intensive and likely impractical during an emergency. Researchers have now developed a comparative genomics strategy to drastically reduce the time needed to accurately identify unique genetic properties of a potential outbreak strain. This report, which demonstrates the approach using next-generation sequencing technology, is published online today in Genome Research (www.genome.org).
4월 2일	Researchers ID gene linked to lung cancer Researchers at Johns Hopkins, as part of a large, multi-institutional study, have found one gene variant that is linked to an increased risk of lung cancer. The study will be published in the April 3 issue of Nature Genetics.

3. 국내외 전문연구동향 (산업동향 포함)

날짜	내용
4월 29일	질병정복의 꿈, '포스트 게놈'…아시아를 잡아라!
4월 28일	政, 유전정보 등 인체자원 직접 관리
4월 24일	보리와 밀에서 형광분석기를 이용한 멀티플렉스 레디 PCR방법 개발
4월 24일	EST 표지를 이용한 사과의 연관지도
4월 23일	옥수수의 연관지도 작성과 통기조직형성관련 QTL 확인
4월 17일	"'IT+BT+NT=첨단의료기'를 조기사업화 하라!"
4월 9일	신장과 유전 정보와의 관계 밝혀져
4월 1일	세계 최초로 흰개미 장내 공생 미생물의 게놈 해독
3월 31일	농업 해충인 바구미의 유전체 해독 완결

4. PubMed에 소개된 생물정보학관련 4월 주요리뷰(편집자 주)

5. PLoS Computational Biology Journals(편집자 주: Editor's Pick)

제목	요약
A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach	Bjoern Peters et al. from La Jolla and California State provide an unbiased ranking of the performance of publicly available MHC class II prediction tools and highlight the binding core identification as a critical issue that limits the prediction performance. PLoS Comput Biol 4(4): e1000048.
The Role of Elastic Stresses on Leaf Venation Morphogenesis	Laguna, Bohn & Jagla explore the idea that elastic stresses play an important role in the development of leaf venation patterns. Through a comparison of actual and simulated patterns, their hypothesis explains the existence of hierarchical structures not accounted for by auxin canalization. PLoS Comput Biol 4(4): e1000055.

6. Bioinformatics 저널 주요논문(편집자 주, IF, 인용지수=4.894)

Number	Title
Bioinformatics Volume 24, Number 7	The effect of sequence quality on sequence alignment
	PCCA: a program for phylogenetic canonical correlation analysis
	Statistical search on the Semantic Web
Bioinformatics Volume 24, Number 8	The Taverna Interaction Service: enabling manual interaction in workflows
	In silico Biochemical Reaction Network Analysis (IBRENA): a package for simulation and analysis of reaction networks

7. BMC Journals
  7-1. BMC Bioinformatics (IF, 인용지수 = 3.62)

제 목	요 약
Integrating proteomic and microarray data BMC Bioinformatics 2008, 9:118	Combining microarray and proteomics datasets at the level of individual exons and isoforms helps to obtain higher correlation between the datasets and to account for alternative splicing.
Scoring function for protein design 2008, 9:148	An extended coulomb/accessible surface area solvent model acts as an empirical scoring function for assessing protein stability and ligand binding affinities in protein structure prediction and computational protein design
Mind the GAPscreener BMC Bioinformatics 2008, 9:205	PubMed abstracts can now be effectively screened for articles related to human genetic association studies and genome epidemiology using GAPscreener, a free java-based tool.

참고: BMC Bioinformatics: Most viewed articles in past 30 days
  7-2. BMC Genomics Research highlights (Impact Factor=4.03)

제 목	요 약
Resequencing genomes improves data quality BMC Genomics 2008, 9:138	Errors in microbial genome sequences are not restricted to point mutations and may also consist of large-scale rearrangements, such as insertions, which should be rectified so that these data can be of continuing use.
SNP panel for rat genetics BMC Genomics 2008, 9:95	A genomewide set of 820 SNP assays developed for a wide range of lab rat strains will ease genetic mapping studies and association studies in this important disease model.
Clever genomic tools for bird brains BMC Genomics 2008, 9:131	The Songbird Neurogenomics initiative (SoNG) provides a genomic database, a set of genomic tools and also a mechanism for community collaboration to enhance research linking the genomics, evolution, neuroscience and behavior of songbirds.

참고: BMC Genomics: Most viewed articles in past 30 days

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